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Stat5b Is Essential for Natural Killer Cell–mediated Proliferation and Cytolytic Activity

We have analyzed the immune system in Stat5-deficient mice. Although Stat5a(−/−) splenocytes have a partial defect in anti-CD3-induced proliferation that can be overcome by high dose interleukin (IL)-2, we now demonstrate that defective proliferation in Stat5b(−/−) splenocytes cannot be corrected by...

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Main Authors: Imada, Kazunori, Bloom, Eda T., Nakajima, Hiroshi, Horvath-Arcidiacono, Judith A., Udy, Garry B., Davey, Helen W., Leonard, Warren J.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212377/
https://ncbi.nlm.nih.gov/pubmed/9841920
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