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Interleukin 4 Gene–defective Mice Reconstituted with Wild-type Bone Marrow Fail to Produce Normal Immunoglobulin E Levels

The ability to reconstitute interleukin (IL)-4(−/−) mice with bone marrow of IL-4(+/+) mice was investigated. The absence of the IL-4(−/−) gene in donor or recipient cells did not impair the reconstitution. All immunoglobulin (Ig) subsets occurred at normal serum levels except for IgE and to some ex...

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Hlavní autoři: Lange, Claudia, Schüler, Thomas, Blankenstein, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212264/
https://ncbi.nlm.nih.gov/pubmed/9565640
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