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Analysis of the human polynucleotide phosphorylase (PNPase) reveals differences in RNA binding and response to phosphate compared to its bacterial and chloroplast counterparts

PNPase is a major exoribonuclease that plays an important role in the degradation, processing, and polyadenylation of RNA in prokaryotes and organelles. This phosphorolytic processive enzyme uses inorganic phosphate and nucleotide diphosphate for degradation and polymerization activities, respective...

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Detalhes bibliográficos
Main Authors: Portnoy, Victoria, Palnizky, Gili, Yehudai-Resheff, Shlomit, Glaser, Fabian, Schuster, Gadi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212259/
https://ncbi.nlm.nih.gov/pubmed/18083836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.698108
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