Analysis of the human polynucleotide phosphorylase (PNPase) reveals differences in RNA binding and response to phosphate compared to its bacterial and chloroplast counterparts

PNPase is a major exoribonuclease that plays an important role in the degradation, processing, and polyadenylation of RNA in prokaryotes and organelles. This phosphorolytic processive enzyme uses inorganic phosphate and nucleotide diphosphate for degradation and polymerization activities, respective...

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Hauptverfasser: Portnoy, Victoria, Palnizky, Gili, Yehudai-Resheff, Shlomit, Glaser, Fabian, Schuster, Gadi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212259/
https://ncbi.nlm.nih.gov/pubmed/18083836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.698108
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