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Analysis of the human polynucleotide phosphorylase (PNPase) reveals differences in RNA binding and response to phosphate compared to its bacterial and chloroplast counterparts

PNPase is a major exoribonuclease that plays an important role in the degradation, processing, and polyadenylation of RNA in prokaryotes and organelles. This phosphorolytic processive enzyme uses inorganic phosphate and nucleotide diphosphate for degradation and polymerization activities, respective...

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Autors principals: Portnoy, Victoria, Palnizky, Gili, Yehudai-Resheff, Shlomit, Glaser, Fabian, Schuster, Gadi
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212259/
https://ncbi.nlm.nih.gov/pubmed/18083836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.698108
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