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The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins

Early in programmed cell death (apoptosis), mitochondrial membrane permeability increases. This is at least in part due to opening of the permeability transition (PT) pore, a multiprotein complex built up at the contact site between the inner and the outer mitochondrial membranes. The PT pore has be...

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Detalhes bibliográficos
Main Authors: Marzo, Isabel, Brenner, Catherine, Zamzami, Naoufal, Susin, Santos A., Beutner, Gisela, Brdiczka, Dieter, Rémy, René, Xie, Zhi-Hua, Reed, John C., Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212234/
https://ncbi.nlm.nih.gov/pubmed/9547337
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