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CD28-independent Induction of T Helper Cells and Immunoglobulin Class Switches Requires Costimulation by the Heat-stable Antigen

It is well established that B7-CD28/CTLA4 interactions play an important role in the induction of T helper cells for T-dependent antibody responses. However, targeted mutation of CD28 does not significantly affect production of IgG and activation of CD4 T helper cells in response to infections by so...

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Autores principales: Wu, Yan, Zhou, Qunmin, Zheng, Pan, Liu, Yang
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212205/
https://ncbi.nlm.nih.gov/pubmed/9529332
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