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Transforming Growth Factor β1, in the Presence of Granulocyte/Macrophage Colony-stimulating Factor and Interleukin 4, Induces Differentiation of Human Peripheral Blood Monocytes into Dendritic Langerhans Cells

Langerhans cells (LCs) are dendritic cells (DCs) that are present in the epidermis, bronchi, and mucosae. Although LCs originate in bone marrow, little is known about their lineage of origin. In this study, we demonstrate that in vitro LCs may originate from monocytes. Adult peripheral blood CD14(+)...

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Main Authors: Geissmann, Frederic, Prost, Catherine, Monnet, Jean-Paul, Dy, Michel, Brousse, Nicole, Hermine, Olivier
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212193/
https://ncbi.nlm.nih.gov/pubmed/9500798
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