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Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells

Freshly isolated, murine epidermal Langerhans cells (LC) are weak accessory cells for primary T cell-dependent immune responses, but increase their stimulatory capacity at least 20-fold progressively over a 3-d culture with keratinocytes. We have studied the mediators of LC maturation. LC enriched f...

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Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188828/
https://ncbi.nlm.nih.gov/pubmed/3279156
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