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Induction of Protective Cytotoxic T Cell Responses in the Presence of High Titers of  Virus-neutralizing Antibodies: Implications for Passive and Active Immunization

The effect of preexistent virus-neutralizing antibodies on the active induction of antiviral T cell responses was studied in two model infections in mice. Against the noncytopathic lymphocytic choriomeningitis virus (LCMV), pretreatment with neutralizing antibodies conferred immediate protection aga...

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Detalhes bibliográficos
Main Authors: Seiler, Peter, Bründler, Marie-Anne, Zimmermann, Christine, Weibel, Doris, Bruns, Michael, Hengartner, Hans, Zinkernagel, Rolf M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212147/
https://ncbi.nlm.nih.gov/pubmed/9463415
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