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Human Autoantibody Silencing by Immunoglobulin Light Chains

Several newly arising human antibodies are polyreactive, but in normal individuals the majority of these potentially autodestructive antibodies are removed from the repertoire by receptor editing or B cell deletion in the bone marrow. To determine what proportion of naturally arising autoantibodies...

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Bibliografiske detaljer
Main Authors: Wardemann, Hedda, Hammersen, Johanna, Nussenzweig, Michel C.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212019/
https://ncbi.nlm.nih.gov/pubmed/15263026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040818
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