Role of Dok-1 and Dok-2 in Myeloid Homeostasis and Suppression of Leukemia

Dok-1 and Dok-2 are closely related rasGAP-associated docking proteins expressed preferentially in hematopoietic cells. Although they are phosphorylated upon activation of many protein tyrosine kinases (PTKs), including those coupled with cytokine receptors and oncogenic PTKs like Bcr-Abl, their phy...

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Bibliographische Detailangaben
Hauptverfasser: Yasuda, Tomoharu, Shirakata, Masaki, Iwama, Atsushi, Ishii, Asuka, Ebihara, Yasuhiro, Osawa, Mitsujiro, Honda, Kazuho, Shinohara, Hisaaki, Sudo, Katsuko, Tsuji, Kohichiro, Nakauchi, Hiromitsu, Iwakura, Yoichiro, Hirai, Hisamaru, Oda, Hideaki, Yamamoto, Tadashi, Yamanashi, Yuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2004
Schlagworte:
Brief Definitive Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211997/
https://ncbi.nlm.nih.gov/pubmed/15611294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041247
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