Differential Requirements for Vav Proteins in DAP10- and ITAM-mediated NK Cell Cytotoxicity

Natural killer (NK) cells express multiple activating receptors that initiate signaling cascades through DAP10- or immunoreceptor tyrosine-based activation motif–containing adapters, including DAP12 and FcRγ. Among downstream signaling mediators, the guanine nucleotide exchange factor Vav1 carries o...

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Main Authors: Cella, Marina, Fujikawa, Keiko, Tassi, Ilaria, Kim, Sunjin, Latinis, Kevin, Nishi, Shinzo, Yokoyama, Wayne, Colonna, Marco, Swat, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2004
Assuntos:
Brief Definitive Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211968/
https://ncbi.nlm.nih.gov/pubmed/15365099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031847
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