Defective Suppressor Function of Human CD4(+) CD25(+) Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II

In autoimmune polyglandular syndromes (APS), several organ-specific autoimmune diseases are clustered. Although APS type I is caused by loss of central tolerance, the etiology of APS type II (APS-II) is currently unknown. However, in several murine models, depletion of CD4(+) CD25(+) regulatory T ce...

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Autores principales: Kriegel, Martin A., Lohmann, Tobias, Gabler, Christoph, Blank, Norbert, Kalden, Joachim R., Lorenz, Hanns-Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2004
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211900/
https://ncbi.nlm.nih.gov/pubmed/15117972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20032158
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