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Central Tolerance to Tissue-specific Antigens Mediated by Direct and Indirect Antigen Presentation
Intrathymic expression of tissue-specific antigens (TSAs) by medullary thymic epithelial cells (Mtecs) leads to deletion of autoreactive T cells. However, because Mtecs are known to be poor antigen-presenting cells (APCs) for tolerance to ubiquitous antigens, and very few Mtecs express a given TSA,...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2004
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211843/ https://ncbi.nlm.nih.gov/pubmed/15492126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041457 |
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