Induction of Tumor-specific T Cell Immunity by Anti-DR5 Antibody Therapy

Because tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) preferentially induces apoptosis in tumor cells and plays a critical role in tumor surveillance, its receptor is an attractive target for antibody-mediated tumor therapy. Here we report that a monoclonal antibody (mAb) against t...

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Main Authors: Takeda, Kazuyoshi, Yamaguchi, Noriko, Akiba, Hisaya, Kojima, Yuko, Hayakawa, Yoshihiro, Tanner, Jane E., Sayers, Thomas J., Seki, Naoko, Okumura, Ko, Yagita, Hideo, Smyth, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211825/
https://ncbi.nlm.nih.gov/pubmed/14769851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031457
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