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Exogenous Pathogen and Plant 15-Lipoxygenase Initiate Endogenous Lipoxin A(4) Biosynthesis

Lipoxin A(4) (LXA(4)) is a potent endogenous lipoxygenase-derived eicosanoid with antiinflammatory and proresolving properties. Supraphysiological levels of LXA(4) are generated during infection by Toxoplasma gondii, which in turn reduces interleukin (IL) 12 production by dendritic cells, thus dampe...

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Detalhes bibliográficos
Main Authors: Bannenberg, Gerard L., Aliberti, Julio, Hong, Song, Sher, Alan, Serhan, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211821/
https://ncbi.nlm.nih.gov/pubmed/14970178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031325
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