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Human Mannose-binding Lectin in Immunity: Friend, Foe, or Both?

Human mannose-binding lectin (MBL) recognizes a wide range of microorganisms and triggers the most ancient pathway of complement activation. However, ∼5% of individuals lack functional serum MBL and have not been found to be prone to severe infections in prospective studies. These data suggest that...

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Bibliografski detalji
Glavni autori: Casanova, Jean-Laurent, Abel, Laurent
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211810/
https://ncbi.nlm.nih.gov/pubmed/15148331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040537
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