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Fibrin(ogen) in human disease: both friend and foe

Fibrinogen is an abundant protein synthesized in the liver, present in human blood plasma at concentrations ranging from 1.5-4 g/L in healthy individuals with a normal half-life of 3-5 days. With fibrin, produced by thrombin-mediated cleavage, fibrinogen plays important roles in many physiological p...

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Bibliografiske detaljer
Udgivet i:Haematologica
Main Authors: Vilar, Rui, Fish, Richard J., Casini, Alessandro, Neerman-Arbez, Marguerite
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012490/
https://ncbi.nlm.nih.gov/pubmed/31949010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.236901
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