Загрузка...

Asymmetric Division and Lineage Commitment at the Level of Hematopoietic Stem Cells: Inference from Differentiation in Daughter Cell and Granddaughter Cell Pairs

How hematopoietic stem cells (HSCs) commit to a particular lineage is unclear. A high degree of HSC purification enabled us to address this issue at the clonal level. Single-cell transplantation studies revealed that 40% of the CD34(−/low), c-Kit(+), Sca-1(+), and lineage marker(−) (CD34(−)KSL) cell...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Takano, Hina, Ema, Hideo, Sudo, Kazuhiro, Nakauchi, Hiromitsu
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2004
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211802/
https://ncbi.nlm.nih.gov/pubmed/14744992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030929
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!