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Short-lived Plasmablasts and Long-lived Plasma Cells Contribute to Chronic Humoral Autoimmunity in NZB/W Mice

The current view holds that chronic autoimmune diseases are driven by the continuous activation of autoreactive B and T lymphocytes. However, despite the use of potent immunosuppressive drugs designed to interfere with this activation the production of autoantibodies often persists and contributes t...

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Autores principales: Hoyer, Bimba F., Moser, Katrin, Hauser, Anja E., Peddinghaus, Anette, Voigt, Caroline, Eilat, Dan, Radbruch, Andreas, Hiepe, Falk, Manz, Rudolf A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211779/
https://ncbi.nlm.nih.gov/pubmed/15173206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040168
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