The Activation Status of Neuroantigen-specific T Cells in the Target Organ Determines the Clinical Outcome of Autoimmune Encephalomyelitis

The clinical picture of experimental autoimmune encephalomyelitis (EAE) is critically dependent on the nature of the target autoantigen and the genetic background of the experimental animals. Potentially lethal EAE is mediated by myelin basic protein (MBP)–specific T cells in Lewis rats, whereas tra...

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Bibliografiset tiedot
Päätekijät: Kawakami, Naoto, Lassmann, Silke, Li, Zhaoxia, Odoardi, Francesca, Ritter, Thomas, Ziemssen, Tjalf, Klinkert, Wolfgang E.F., Ellwart, Joachim W., Bradl, Monika, Krivacic, Kimberly, Lassmann, Hans, Ransohoff, Richard M., Volk, Hans-Dieter, Wekerle, Hartmut, Linington, Christopher, Flügel, Alexander
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2004
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211765/
https://ncbi.nlm.nih.gov/pubmed/14734524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031064
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