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Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis

i.v. infusion of native autoantigen or its altered peptide variants is an important therapeutic option for the treatment of autoimmune diseases, because it selectively targets the disease-inducing T cells. To learn more about the mechanisms and kinetics of this approach, we visualized the crucial in...

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Detalhes bibliográficos
Main Authors: Odoardi, Francesca, Kawakami, Naoto, Li, Zhaoxia, Cordiglieri, Chiara, Streyl, Kristina, Nosov, Mikhail, Klinkert, Wolfgang E. F., Ellwart, Joachim W., Bauer, Jan, Lassmann, Hans, Wekerle, Hartmut, Flügel, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783415/
https://ncbi.nlm.nih.gov/pubmed/17213317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608383104
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