Stage-specific differences in the requirements for germline stem cell maintenance in the Drosophila ovary

In this study, we uncover a role for microRNAs in Drosophila germline stem cell (GSC) maintenance. Disruption of Dicer-1 function in GSCs during adult life results in GSC loss. Surprisingly, however, loss of Dicer-1 during development does not result in a GSC maintenance defect, although a defect is...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Shcherbata, Halyna R., Ward, Ellen J., Fischer, Karin A., Yu, Jenn-Yah, Reynolds, Steven H., Chen, Chun-Hong, Xu, Peizhang, Hay, Bruce A., Ruohola-Baker, Hannele
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211735/
https://ncbi.nlm.nih.gov/pubmed/18213359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2007.11.007
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