A Mosaic Fiber Adenovirus Serotype 5 Vector Containing Reovirus σ1 and Adenovirus Serotype 3 Knob Fibers Increases Transduction in an Ovarian Cancer Ex vivo System via a Coxsackie and Adenovirus Receptor-Independent Pathway

PURPOSE: Adenovirus serotype 5 (Ad5) has been used for gene therapy with limited success due to insufficient infectivity in cells with low expression of the primary receptor, the coxsackie and adenovirus receptor (CAR). Evidence that adenovirus serotype receptors other than CAR may be of use was pre...

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Detalhes bibliográficos
Main Authors: Tsuruta, Yuko, Pereboeva, Larisa, Glasgow, Joel N., Rein, Daniel T., Kawakami, Yosuke, Alvarez, Ronald D., Rocconi, Rodney P., Siegal, Gene P., Dent, Paul, Fisher, Paul B., Curiel, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211731/
https://ncbi.nlm.nih.gov/pubmed/17473211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-2706
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