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Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates
In budding yeast, phosphate starvation triggers inhibition of the Pho80-Pho85 cyclin–cyclin-dependent kinase (CDK) complex by the CDK inhibitor Pho81, leading to expression of genes involved in nutrient homeostasis. We isolated myo-d-inositol heptakisphosphate (IP(7)) as a cellular component that st...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211727/ https://ncbi.nlm.nih.gov/pubmed/17412959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1139080 |
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