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The HCMV Gene Products US11 and US2 Differ in Their Ability to Attack Allelic Forms of Murine Major Histocompatibility Complex (MHC) Class I Heavy Chains

Human cytomegalovirus downregulates the expression of human class I major histocompatibility complex (MHC) molecules by accelerating destruction of newly synthesized class I heavy chains. The HCMV genome contains at least two genes, US11 and US2, each of which encode a product sufficient for causing...

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Main Authors: Machold, Robert P., Wiertz, Emmanuel J.H.J., Jones, Thomas R., Ploegh, H.L.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211711/
https://ncbi.nlm.nih.gov/pubmed/9016885
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