Wordt geladen...

Short-lived protease–serpin complexes: Partial disruption of the rat trypsin active site

Serpins inhibit serine proteases by mechanically disrupting the protease active site. The protease first reacts with the serpin's reactive center loop (RCL) to form an acylenzyme. Then the RCL inserts into a β-sheet in the body of the serpin, translocating the attached protease ∼70 Å and deform...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Liu, Lu, Mushero, Nicole, Hedstrom, Lizbeth, Gershenson, Anne
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211700/
https://ncbi.nlm.nih.gov/pubmed/17962402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073111207
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!