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Elimination of Rapid Potassium Channel Inactivation by Phosphorylation of the Inactivation Gate

The effect of protein kinase C (PKC) on rapid N-type inactivation of K(+) channels has not been reported previously. We found that PKC specifically eliminates rapid inactivation of a cloned human A-type K(+) channel (hKv3.4), converting this channel from a rapidly inactivating A type to a noninactiv...

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Detalhes bibliográficos
Main Authors: Covarrubias, Manuel, Wei, Aguan, Salkoff, Lawrence, Vyas, Tapan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211371/
https://ncbi.nlm.nih.gov/pubmed/7993631
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