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Rapid Determination of Enzyme Kinetics from Fluorescence: Overcoming the Inner Filter Effect

Fluorescence change is convenient for monitoring enzyme kinetics. Unfortunately, it looses linearity as the absorbance of the fluorescent substrate increases with concentration. When the sum of absorbance at excitation and emission wavelengths exceeds 0.08, this inner filtering effect (IFE) alters a...

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Detalhes bibliográficos
Main Authors: Palmier, Mark O., Van Doren, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211277/
https://ncbi.nlm.nih.gov/pubmed/17706587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.07.008
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