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Comparing the structure and dynamics of phospholamban pentamer in its unphosphorylated and pseudo-phosphorylated states
Human phospholamban (PLN), a 30 kDa homopentamer in the sarcoplasmic reticulum (SR) membrane, controls the magnitude of heart muscle contraction and relaxation by regulating the calcium pumping activity of the SR Ca(2+)-ATPase (SERCA). When PLN is not phosphorylated, it binds and inhibits SERCA. Pho...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley-Blackwell
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206959/ https://ncbi.nlm.nih.gov/pubmed/17766390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072975107 |
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