GnRH and LHR gene variants predict adverse outcome in premenopausal breast cancer patients

BACKGROUND: Breast cancer development and progression are dependent on estrogen activity. In premenopausal women, estrogen production is mainly regulated through the hypothalamic-pituitary-gonadal (HPG) axis. METHODS: We have investigated the prognostic significance of two variants of genes involved...

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Detalhes bibliográficos
Main Authors: Piersma, Djura, Themmen, Axel PN, Look, Maxime P, Klijn, Jan GM, Foekens, John A, Uitterlinden, André G, Pols, Huibert AP, Berns, Els MJJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206727/
https://ncbi.nlm.nih.gov/pubmed/17692113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1756
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