Adenovirus type 5 E1A-induced apoptosis in COX-2-overexpressing breast cancer cells

INTRODUCTION: Suppression of Bcl-2 expression can overcome cellular resistance to apoptosis induced by the adenovirus type 5 gene E1A in models of ovarian and breast cancer. Celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, is known to downregulate Bcl-2 expression. We hypothesized that celecoxib wou...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sugimoto, Takeshi, Bartholomeusz, Chandra, Tari, Ana M, Ueno, Naoto T
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206712/
https://ncbi.nlm.nih.gov/pubmed/17612393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1739
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires