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Adenovirus type 5 E1A-induced apoptosis in COX-2-overexpressing breast cancer cells
INTRODUCTION: Suppression of Bcl-2 expression can overcome cellular resistance to apoptosis induced by the adenovirus type 5 gene E1A in models of ovarian and breast cancer. Celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, is known to downregulate Bcl-2 expression. We hypothesized that celecoxib wou...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206712/ https://ncbi.nlm.nih.gov/pubmed/17612393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1739 |
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