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Functional structure of the somatomedin B domain of vitronectin
The N-terminal somatomedin B domain (SMB) of vitronectin binds PAI-1 and the urokinase receptor with high affinity and regulates tumor cell adhesion and migration. We have shown previously in the crystal structure of the PAI-1/SMB complex that SMB, a peptide of 51 residues, is folded as a compact cy...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206693/ https://ncbi.nlm.nih.gov/pubmed/17567740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072819107 |
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