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Similarities in the thermodynamics and kinetics of aggregation of disease-related Aβ(1–40) peptides

Increasing evidence indicates that polypeptide aggregation often involves a nucleation and a growth phase, although the relationship between the factors that determine these two phases has not yet been fully clarified. We present here an analysis of several mutations at different sites of the Aβ(1–4...

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Autores principales: Meinhardt, Jessica, Tartaglia, Gian Gaetano, Pawar, Amol, Christopeit, Tony, Hortschansky, Peter, Schroeckh, Volker, Dobson, Christopher M., Vendruscolo, Michele, Fändrich, Marcus
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206661/
https://ncbi.nlm.nih.gov/pubmed/17525469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062734207
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