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Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold
Pathogenic members of the flavivirus family, including West Nile Virus (WNV) and Dengue Virus (DV), are growing global threats for which there are no specific treatments. The two-component flaviviral enzyme NS2B-NS3 cleaves the viral polyprotein precursor within the host cell, a process that is requ...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206648/ https://ncbi.nlm.nih.gov/pubmed/17400917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072753207 |
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