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Inter-ring communication allows the GroEL chaperonin complex to distinguish between different substrates
The productive folding of substrate proteins by the GroEL complex of Escherichia coli requires the activity of both the chaperonin rings. These heptameric rings were shown to regulate the chaperonins’ affinity for substrates and co-chaperonin via inter-ring communications; however, the molecular det...
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Main Authors: | , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Cold Spring Harbor Laboratory Press
2007
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206630/ https://ncbi.nlm.nih.gov/pubmed/17456746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062713607 |
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