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cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

The turnover of cholesterol in the brain is thought to occur via conversion of excess cholesterol into 24S-hydroxycholesterol, an oxysterol that is readily secreted from the central nervous system into the plasma. To gain molecular insight into this pathway of cholesterol metabolism, we used express...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lund, Erik G., Guileyardo, Joseph M., Russell, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22064/
https://ncbi.nlm.nih.gov/pubmed/10377398
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