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cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

The turnover of cholesterol in the brain is thought to occur via conversion of excess cholesterol into 24S-hydroxycholesterol, an oxysterol that is readily secreted from the central nervous system into the plasma. To gain molecular insight into this pathway of cholesterol metabolism, we used express...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lund, Erik G., Guileyardo, Joseph M., Russell, David W.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1999
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22064/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377398/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.13.7238
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