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Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors α and β

Estrogen-based drug therapy in cardiovascular diseases has been difficult because it has not been possible to separate the wanted vasculoprotective effect from the unwanted effects of the hormone to the reproductive system. Here, we demonstrate that, after endothelial denudation of rat carotid arter...

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Detalhes bibliográficos
Main Authors: Mäkelä, Sari, Savolainen, Hanna, Aavik, Einari, Myllärniemi, Marjukka, Strauss, Leena, Taskinen, Eero, Gustafsson, Jan-Åke, Häyry, Pekka
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22061/
https://ncbi.nlm.nih.gov/pubmed/10359841
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