Delay of Postnatal Maturation Sensitizes the Mouse Prostate to Testosterone-Induced Pronounced Hyperplasia : Protective Role of Estrogen Receptor-β

The role of estrogens in the etiology of prostate cancer is controversial. To demonstrate the specific effects of estrogens and androgens on the development of the prostatic epithelial hyperplasia, we used luteinizing hormone receptor knockout mice (LuRKO), which are resistant to pituitary regulatio...

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Detalhes bibliográficos
Main Authors: Savolainen, Saija, Pakarainen, Tomi, Huhtaniemi, Ilpo, Poutanen, Matti, Mäkelä, Sari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959505/
https://ncbi.nlm.nih.gov/pubmed/17640960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060979
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