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Identification of SH2-Bβ as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2

Janus kinases (JAKs) are cytoplasmic tyrosine kinases critical for signaling by growth hormone (GH) and many other ligands that bind to members of the cytokine receptor superfamily. SH2-Bβ was previously identified as a JAK2-interacting protein that is tyrosyl phosphorylated in response to GH and ot...

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Библиографические подробности
Главные авторы: Rui, Liangyou, Carter-Su, Christin
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC22043/
https://ncbi.nlm.nih.gov/pubmed/10377387
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