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Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein

We report the design and engineering of a robust, reagentless fluorescent glucose biosensor based on the periplasmic glucose-binding protein obtained from Thermotoga maritima (tmGBP). The gene for this protein was cloned from genomic DNA and overexpressed in Escherichia coli, the identity of its cog...

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Autores principales: Tian, Yaji, Cuneo, Matthew J., Changela, Anita, Höcker, Birte, Beese, Lorena S., Hellinga, Homme W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2204141/
https://ncbi.nlm.nih.gov/pubmed/17766373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072969407
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