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Optimal design and validation of antiviral siRNA for targeting HIV-1
We propose rational designing of antiviral short-interfering RNA (siRNA) targeting highly divergent HIV-1. In this study, conserved regions within HIV-1 genomes were identified through an exhaustive computational analysis, and the functionality of siRNAs targeting the highest possible conserved regi...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2204037/ https://ncbi.nlm.nih.gov/pubmed/17996047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-80 |
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