Revealing biases inherent in recombination protocols

BACKGROUND: The recombination of homologous genes is an effective protein engineering tool to evolve proteins. DNA shuffling by gene fragmentation and reassembly has dominated the literature since its first publication, but this fragmentation-based method is labor intensive. Recently, a fragmentatio...

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Detaylı Bibliyografya
Asıl Yazarlar: Chaparro-Riggers, Javier F, Loo, Bernard LW, Polizzi, Karen M, Gibbs, Phillip R, Tang, Xiao-Song, Nelson, Mark J, Bommarius, Andreas S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2007
Konular:
Methodology Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203992/
https://ncbi.nlm.nih.gov/pubmed/18001472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-77
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