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Specific interactions of serpins in their native forms attenuate their conformational transitions

Plasminogen activator inhibitor-1 (PAI-1) belongs to the serine protease inhibitor (serpin) protein superfamily. Serpins are unique in that their native forms are not the most thermodynamically stable conformation; instead, a more stable, latent conformation exists. During the transition to the late...

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Detalles Bibliográficos
Autores principales: Na, Yu-Ran, Im, Hana
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203359/
https://ncbi.nlm.nih.gov/pubmed/17600149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072838107
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