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Important roles of hydroxylic amino acid residues in the function of Bacillus subtilis adenylosuccinate lyase
Thr(93), Ser(94), Thr(140), and Ser(306) are conserved in all adenylosuccinate lyases (ASL) and are close to other amino acids previously identified by mutagenesis as being in the active site. To test their involvement in the enzyme's function, each of these amino acids was replaced by alanine....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2203318/ https://ncbi.nlm.nih.gov/pubmed/17322529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062650007 |
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