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Domain motions of glucosamine-6P synthase: Comparison of the anisotropic displacements in the crystals and the catalytic hinge-bending rotation

Glucosamine-6-phosphate synthase channels ammonia over 18 Å from glutamine at the glutaminase site to fructose-6P at the synthase site. We have modeled the anisotropic displacements of the glutaminase and synthase domains from the two crystallized states, the enzyme in complex with fructose-6P or in...

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Bibliographic Details
Main Authors: Mouilleron, Stéphane, Golinelli-Pimpaneau, Béatrice
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203311/
https://ncbi.nlm.nih.gov/pubmed/17322533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062598107
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