Lysine 58-cleaved β2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis

The lysine 58 cleaved and truncated variant of β(2)-microglobulin (ΔK58-β2m) is conformationally unstable and present in the circulation of a large percentage of patients on chronic hemodialysis, suggesting that it could play a role in the β2-microglobulin (β2m) amyloid fibrillogenesis associated wi...

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Bibliografische gegevens
Hoofdauteurs: Giorgetti, Sofia, Stoppini, Monica, Tennent, Glenys A., Relini, Annalisa, Marchese, Loredana, Raimondi, Sara, Monti, Maria, Marini, Sara, Østergaard, Ole, Heegaard, Niels H.H., Pucci, Piero, Esposito, Gennaro, Merlini, Giampaolo, Bellotti, Vittorio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203293/
https://ncbi.nlm.nih.gov/pubmed/17242436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062563507
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