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Is glycine a surrogate for a d-amino acid in the collagen triple helix?

Collagen is the most abundant protein in animals. Every third residue in a collagen strand is a glycine with ϕ, ψ = −70°, 175°. A recent computational study suggested that replacing these glycine residues with d-alanine or d-serine would stabilize the collagen triple helix. This hypothesis is of sub...

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Autores principales: Horng, Jia-Cherng, Kotch, Frank W., Raines, Ronald T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203290/
https://ncbi.nlm.nih.gov/pubmed/17189476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062560107
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